产品货号:
Z24252
中文名称:
PPM1F抗体
英文名称:
Anti-PPM1F Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-PPM1F Antibody |
指标别名 | PPM1F;KIAA0015;POPX2;Protein phosphatase 1F;Ca(2+)/calmodulin-dependent protein kinase phosphatase;CaM-kinase phosphatase;CaMKPase;Partner of PIX 2;Protein fem-2 homolog;hFem-2 |
克隆性 | Polyclonal |
检验物种 | human |
应用范围 | WB,ICC/IF,Direct ELISA |
基因名称 | PPM1F |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | E.coli-derived human PPM1F recombinant protein (Position:E17-S454). |
实际分子量 | 54KD |
成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
纯化方式 | Immunogen affinity purified. |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | Protein phosphatase 1F is an enzyme that in humans is encoded by the PPM1F gene.The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases.PP2C family members are known to be negative regulators of cell stress response pathways.This phosphatase can interact with Rho guanine nucleotide exchange factors (PIX),and thus block the effects of p21-activated kinase 1 (PAK),a protein kinase mediating biological effects downstream of Rho GTPases.Calcium/calmodulin-dependent protein kinase II gamma (CAMK2G/CAMK-II) is found to be one of the substrates of this phosphatase.The overexpression of this phosphatase or CAMK2G has been shown to mediate caspase-dependent apoptosis.An alternatively spliced transcript variant has been identified,but its full-length nature has not been determined. |
Uniprot ID | P49593 |
推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for ICC. |
基因名全称 | protein phosphatase,Mg2+/Mn2+ dependent 1F |
蛋白名全称 | Protein phosphatase 1F |
推荐稀释比 | Western blot (WB) 1:500~2000 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50~400 Direct ELISA 1:100~1000 |
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